The FCER1G Polyclonal Antibody (CAB12889) is a vital tool for researchers studying FCER1G, a key molecule involved in immune responses and signal transduction. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the FCER1G protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it ideal for investigations in immunology and cancer research.
FCER1G, also known as the high-affinity IgE receptor subunit gamma, plays a crucial role in activating mast cells and basophils in response to allergens and pathogens. Its involvement in immune signaling pathways makes it a valuable target for research on inflammatory diseases, allergies, and immune disorders. Understanding the function of FCER1G is essential for developing targeted therapies that can modulate immune responses and improve treatment outcomes in these conditions.
Product Name:
FCER1G Rabbit Polyclonal Antibody
SKU:
CAB12889
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 19-86 of human FCER1G (NP_004097.1).
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
10kDa
Observed MW:
12kDa
The high affinity IgE receptor is a key molecule involved in allergic reactions. It is a tetramer composed of 1 alpha, 1 beta, and 2 gamma chains. The gamma chains are also subunits of other Fc receptors.
Purification Method:
Affinity purification
Gene ID:
2207
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse spleen, using FCER1G Rabbit pAb (CAB12889) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
