The FCER1A Polyclonal Antibody (CAB1751) is a high-quality tool for researchers studying FCER1A, a protein involved in immune signaling and allergic reactions. This antibody, produced in rabbits, is specifically designed to recognize FCER1A in human samples and is validated for use in Western blot experiments. By binding to FCER1A, this antibody enables precise detection and analysis of the protein in various cell types, making it an essential tool for investigations in immunology and allergy research.FCER1A, also known as the high-affinity IgE receptor alpha subunit, plays a crucial role in allergic responses by mediating the release of inflammatory molecules in response to allergen exposure.
Dysregulation of FCER1A signaling has been implicated in allergic diseases such as asthma, eczema, and allergic rhinitis. By understanding the function and regulation of FCER1A, researchers can develop potential therapeutic strategies for managing allergic conditions and modulating immune responses.Overall, the FCER1A Polyclonal Antibody (CAB1751) is a reliable reagent for investigating the role of FCER1A in immune activation and allergic inflammation, providing valuable insights into potential targets for therapeutic intervention in allergic diseases.
Product Name:
FCER1A Rabbit Polyclonal Antibody
SKU:
CAB1751
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 26-205 of human FCER1A (NP_001992.1).
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
30kDa
Observed MW:
68kDa
The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. This receptor is comprised of an alpha subunit, a beta subunit, and two gamma subunits. The protein encoded by this gene represents the alpha subunit.
Purification Method:
Affinity purification
Gene ID:
2205
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using FCER1A antibody (CAB1751).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).
