The FCER1 Alpha Monoclonal Antibody is a cutting-edge research tool designed for investigating FCER1 Alpha, a cell surface receptor involved in immune response regulation. This monoclonal antibody, produced using advanced technology, exhibits high specificity and sensitivity towards FCER1 Alpha in human samples, making it an ideal choice for various research applications including Western blotting.FCER1 Alpha, also known as Fc epsilon RI alpha chain, plays a crucial role in the activation of mast cells and basophils, key players in allergic reactions and inflammatory responses. By targeting FCER1 Alpha, researchers can gain valuable insights into the mechanisms underlying allergic diseases, asthma, and other immune-mediated disorders.
This antibody empowers scientists to study FCER1 Alpha expression and function in different cell types, facilitating a deeper understanding of its involvement in immune regulation and disease pathology.With its proven performance and reliability in laboratory experiments, the FCER1 Alpha Monoclonal Antibody is a valuable asset for studies in immunology, allergy research, and drug development. By uncovering the intricate workings of FCER1 Alpha, researchers can pave the way for novel therapeutic strategies aimed at modulating immune responses and addressing unmet medical needs in the field of immunology.
Product Name:
FceR1 alpha Monoclonal Antibody
SKU:
CAB22729
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant protein of human FceR1 alpha.
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:1000 - 1:7000
Synonyms:
FCE1A; FcERI; FCERIA; FceR1 alpha
Positive Sample:
HEL,RAW264.7,Rat thymus
Conjugate:
Unconjugated
Cellular Localization:
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
30kDa
Observed MW:
45-70kDa
The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. This receptor is comprised of an alpha subunit, a beta subunit, and two gamma subunits. The protein encoded by this gene represents the alpha subunit.
Purification Method:
Affinity purification
Gene ID:
2205
Clone Number:
ARC58693
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using FceR1 alpha antibody (CAB22729) at 1:6000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
