The FCAR Polyclonal Antibody (CAB8888) is an essential tool for researchers studying FCAR, also known as the Fc receptor for IgA. This cell surface receptor is involved in the binding and uptake of IgA antibodies, playing a crucial role in immune response and regulation.Raised in rabbits, this antibody is highly specific and reactive with human samples, making it ideal for use in Western blot applications. By binding to the FCAR protein, researchers can accurately detect and analyze FCAR expression in various cell types, helping to further understand its role in immunity and potential implications in diseases such as infections, autoimmune disorders, and inflammatory conditions.
The FCAR Polyclonal Antibody (CAB8888) is a valuable tool for scientists working in immunology, infectious diseases, and autoimmunity research. By studying the function and regulation of FCAR, researchers can gain valuable insights into the immune system's response to pathogens and develop novel therapeutic strategies targeting FCAR for disease treatment and management.
Product Name:
FCAR Rabbit Polyclonal Antibody
SKU:
CAB8888
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 60-287 of human FCAR (NP_001991.1).
Cell membrane, Secreted, Single-pass type I membrane protein.
Calculated MW:
32kDa
Observed MW:
40kDa
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Purification Method:
Affinity purification
Gene ID:
2204
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from 293T cells, using FCAR Rabbit pAb (CAB8888).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
