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FCAR Rabbit Polyclonal Antibody (CAB8888)

SKU:
CAB8888
Product Type:
Antibody
Applications:
WB
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
€139 - €419
Frequently bought together:

Description

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Product Name:FCAR Rabbit Polyclonal Antibody
SKU:CAB8888
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 60-287 of human FCAR (NP_001991.1).
Sequence:LMII KNST YREI GRRL KFWN ETDP EFVI DHMD ANKA GRYQ CQYR IGHY RFRY SDTL ELVV TGLY GKPF LSAD RGLV LMPG ENIS LTCS SAHI PFDR FSLA KEGE LSLP QHQS GEHP ANFS LGPV DLNV SGIY RCYG WYNR SPYL WSFP SNAL ELVV TDSI HQDY TTQN LIRM AVAG LVLV ALLA ILVE NWHS HTAL NKEA SADV AEPS WSQQ MCQP GLTF ARTP SVCK
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:200 - 1:1000 IF/ICC,1:50 - 1:200
Synonyms:CD89; FcalphaR; FcalphaRI; CTB-61M7.2; FCAR
Positive Sample:293T
Conjugate:Unconjugated
Cellular Localization:Cell membrane, Secreted, Single-pass type I membrane protein.
Calculated MW:32kDa
Observed MW:40kDa

This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Purification Method:Affinity purification
Gene ID:2204
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from 293T cells, using FCAR Rabbit pAb (CAB8888).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.

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