FBXW2 Rabbit Polyclonal Antibody (CAB15996)
- SKU:
- CAB15996
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
Product Name: | FBXW2 Rabbit Polyclonal Antibody |
SKU: | CAB15996 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 102-454 of human FBXW2 (NP_036296.2). |
Sequence: | CKNL GWQI DDSV QDAL HWKK VYLK AILR MKQL EDHE AFET SSLI GHSA RVYA LYYK DGLL CTGS DDLS AKLW DVST GQCV YGIQ THTC AAVK FDEQ KLVT GSFD NTVA CWEW SSGA RTQH FRGH TGAV FSVD YNDE LDIL VSGS ADFT VKVW ALSA GTCL NTLT GHTE WVTK VVLQ KCKV KSLL HSPG DYIL LSAD KYEI KIWP IGRE INCK CLKT LSVS EDRS ICLQ PRLH FDGK YIVC SSAL GLYQ WDFA SYDI LRVI KTPE IANL ALLG FGDI FALL FDNR YLYI MDLR TESL ISRW PLPE YRKS KRGS SFLA GEAS WLNG LDGH NDTG LVFA TSMP DHSI HLVL WKEH G |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | Md6; FBW2; Fwd2; FBXW2 |
Positive Sample: | Mouse kidney,Rat kidney,Jurkat |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol |
Calculated MW: | 52kDa |
Observed MW: | 51kDa/52kDa |
F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats, leucine-rich repeats, or the presence or absence of other protein-protein interacting domains. This gene encodes the second identified member of the F-box gene family and contains multiple WD-40 repeats.
Purification Method: | Affinity purification |
Gene ID: | 26190 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |