The FBXO9 Polyclonal Antibody (PACO9260) is a valuable tool for researchers studying the FBXO9 protein, a component of the Skp1-Cullin1-F-box (SCF) complex involved in protein degradation. This antibody, produced in rabbits, demonstrates high specificity and sensitivity in detecting FBXO9 in human samples, making it an ideal choice for Western blot analyses.FBXO9 plays a critical role in targeting specific proteins for degradation via the ubiquitin-proteasome pathway, making it essential for the regulation of various cellular processes.
Research on FBXO9 is vital for understanding protein turnover, cell cycle regulation, and protein quality control mechanisms.By utilizing the FBXO9 Polyclonal Antibody in your experiments, you can gain valuable insights into the function of FBXO9 in cellular processes, making it a valuable tool for studies in molecular biology, cell biology, and cancer research. Unlock the potential of your research with this reliable antibody designed to enhance your understanding of FBXO9 and its role in cellular physiology.
F-box protein 9;FBXO9;DKFZp434C0118;FBX9;KIAA0936;NY-REN-57;VCIA1;dJ341E18.2 ;
UniProt Protein Function:
FBXO9: Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Ubiquitin conjugating system; LigaseChromosomal Location of Human Ortholog: 6p12.3-p11.2Cellular Component: cytoplasm; SCF ubiquitin ligase complex; ubiquitin ligase complexMolecular Function: protein binding; ubiquitin-protein ligase activityBiological Process: fat cell differentiation; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; innate immune response; protein ubiquitination; regulation of TOR signaling pathway
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates at least 3 transcript variants diverging at the 5' terminus. [provided by RefSeq, Jul 2008]
