FBXO7 Rabbit Polyclonal Antibody (CAB7464)
- SKU:
- CAB7464
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
Product Name: | FBXO7 Rabbit Polyclonal Antibody |
SKU: | CAB7464 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 353-522 of human FBXO7 (NP_036311.3). |
Sequence: | LSLS AVCR DLFT ASND PLLW RFLY LRDF RDNT VRVQ DTDW KELY RKRH IQRK ESPK GRFV MLLP SSTH TIPF YPNP LHPR PFPS SRLP PGII GGEY DQRP TLPY VGDP ISSL IPGP GETP SQFP PLRP RFDP VGPL PGPN PILP GRGG PNDR FPFR PSRG RPTD GRLS FM |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IF/ICC,1:50 - 1:200 |
Synonyms: | FBX; FBX7; PKPS; FBX07; PARK15; FBXO7 |
Positive Sample: | U2OS,293T |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Mitochondrion, Nucleus, cytosol. |
Calculated MW: | 59kDa |
Observed MW: | 65-72kDa |
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it may play a role in regulation of hematopoiesis. Alternatively spliced transcript variants of this gene have been identified with the full-length natures of only some variants being determined.
Purification Method: | Affinity purification |
Gene ID: | 25793 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |