FBXO5 Rabbit Polyclonal Antibody (CAB18449)
- SKU:
- CAB18449
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | FBXO5 Rabbit Polyclonal Antibody |
SKU: | CAB18449 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human FBXO5 (NP_036309.1). |
Sequence: | MSRR PCSC ALRP PRCS CSAS PSAV TAAG RPRP SDSC KEES STLS VKMK CDFN CNHV HSGL KLVK PDDI GRLV SYTP AYLE GSCK DCIK DYER LSCI GSPI VSPR IVQL ETES KRLH NKEN QHVQ QTLN STNE IEAL ETSR LYED SGYS SFSL QSGL SEHE EGSL LEEN FGDS LQSC LLQI QSPD QYPN KNLL PVLH FEKV VCST LKKN AKRN PKVD REML KEII ARGN FRLQ NIIG RKMG LECV DILS EL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | EMI1; FBX5; Fbxo31; FBXO5 |
Positive Sample: | Mouse kidney,Rat liver,Rat kidney |
Cellular Localization: | cytoplasm, cytosol, meiotic spindle, nucleoplasm, nucleus, spindle |
Calculated MW: | 50kDa |
Observed MW: | 56kDa |
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is similar to xenopus early mitotic inhibitor-1 (Emi1), which is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. Alternatively spliced transcript variants encoding different isoforms have been identified.
Purification Method: | Affinity purification |
Gene ID: | 26271 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |