The FBXO33 Polyclonal Antibody (CAB14303) is a valuable tool for researchers studying FBXO33, a protein involved in cell cycle regulation and protein degradation pathways. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the FBXO33 protein, it enables researchers to detect and analyze its expression in various cell types, making it an essential component for studies in cancer biology and cell signaling.FBXO33, a member of the F-box protein family, plays a crucial role in targeting proteins for ubiquitination and subsequent degradation by the proteasome.
Its involvement in regulating cell division and cell growth processes makes it a promising target for research into cancer development and progression. By understanding the function of FBXO33, researchers can gain insights into the mechanisms underlying tumorigenesis and potentially identify novel therapeutic targets for cancer treatment.Overall, the FBXO33 Polyclonal Antibody (CAB14303) serves as a reliable tool for investigating the role of FBXO33 in cellular processes and disease pathways, offering valuable insights that could lead to advancements in cancer research and drug discovery efforts.
Product Name:
FBXO33 Rabbit Polyclonal Antibody
SKU:
CAB14303
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 346-555 of human FBXO33 (NP_976046.1).
This locus represents an member of the F-box gene family. The encoded protein contains an F-box motif and a domain that might form a structure similar to a leucine-rich repeat found in placental RNAse inhibitor. This locus may be associated with copy number variation of UGT2B17 (GeneID 7367), which has been associated with susceptibility to osteoporosis.
Purification Method:
Affinity purification
Gene ID:
254170
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using FBXO33 Rabbit pAb (CAB14303) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 20s.
