Fbx32/FBOX32 Rabbit Polyclonal Antibody (CAB11439)
- SKU:
- CAB11439
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
Product Name: | Fbx32/FBOX32 Rabbit Polyclonal Antibody |
SKU: | CAB11439 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 206-355 of human Fbx32/FBXO32 (NP_478136.1). |
Sequence: | WQQQ LNNI QITR PAFK GLTF TDLP LCLQ LNIM QRLS DGRD LVSL GQAA PDLH VLSE DRLL WKKL CQYH FSER QIRK RLIL SDKG QLDW KKMY FKLV RCYP RKEQ YGDT LQLC KHCH ILSW KGTD HPCT ANNP ESCS VSLS PQDF INLF KF |
Tested Applications: | IF/ICC ELISA |
Recommended Dilution: | IF/ICC,1:50 - 1:200 |
Synonyms: | Fbx32; MAFbx; Fbx32/FBXO32 |
Positive Sample: | Mouse ovary |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 42kDa |
Observed MW: | 42kDa |
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 114907 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |