The FBXO31 Polyclonal Antibody (CAB12888) is a valuable tool for researchers studying FBXO31, a protein involved in cellular processes such as protein degradation and cell cycle regulation. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the FBXO31 protein, this antibody enables detection and analysis in various cell types, making it an essential reagent for studies in cell biology and cancer research.FBXO31, a member of the F-box protein family, plays a critical role in regulating the turnover of specific proteins within the cell, thereby influencing various cellular pathways and processes.
Its involvement in protein degradation and cell cycle control highlights its importance in maintaining cellular homeostasis and responding to external stimuli. Research on FBXO31 has implications for understanding disease mechanisms and developing targeted therapies for conditions such as cancer and neurodegenerative disorders.Overall, the FBXO31 Polyclonal Antibody (CAB12888) provides researchers with a robust tool for investigating the functions and regulatory mechanisms of the FBXO31 protein, paving the way for advancements in cellular biology and disease research.
Product Name:
FBXO31 Rabbit Polyclonal Antibody
SKU:
CAB12888
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 240-539 of human FBXO31 (NP_079011.3).
This gene is a member of the F-box family. Members are classified into three classes according to the substrate interaction domain, FBW for WD40 repeats, FBL for leucing-rich repeats, and FBXO for other domains. This protein, classified into the last category because of the lack of a recognizable substrate binding domain, has been proposed to be a component of the SCF ubiquitination complex. It is thought to bind and recruit substrate for ubiquitination and degradation. This protein may have a role in regulating the cell cycle as well as dendrite growth and neuronal migration. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
79791
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using FBXO31 Rabbit pAb (CAB12888) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
