FBXO31 Rabbit Polyclonal Antibody (CAB12888)
- SKU:
- CAB12888
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | FBXO31 Rabbit Polyclonal Antibody |
SKU: | CAB12888 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 240-539 of human FBXO31 (NP_079011.3). |
Sequence: | GGRQ EEFR TWLR EEWG RTLE DIFH EHMQ ELIL MKFI YTSQ YDNC LTYR RIYL PPSR PDDL IKPG LFKG TYGS HGLE IVML SFHG RRAR GTKI TGDP NIPA GQQT VEID LRHR IQLP DLEN QRNF NELS RIVL EVRE RVRQ EQQE GGHE AGEG RGRQ GPRE SQPS PAQP RAEA PSKG PDGT PGED GGEP GDAV AAAE QPAQ CGQG QPFV LPVG VSSR NEDY PRTC RMCF YGTG LIAG HGFT SPER TPGV FILF DEDR FGFV WLEL KSFS LYSR VQAT FRNA DAPS PQAF DEML KNIQ SLTS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | FBX14; Fbx31; MRT45; FBXO14; pp2386; FBXO31 |
Positive Sample: | Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | centrosome, cytosol |
Calculated MW: | 61kDa |
Observed MW: | 60kDa |
This gene is a member of the F-box family. Members are classified into three classes according to the substrate interaction domain, FBW for WD40 repeats, FBL for leucing-rich repeats, and FBXO for other domains. This protein, classified into the last category because of the lack of a recognizable substrate binding domain, has been proposed to be a component of the SCF ubiquitination complex. It is thought to bind and recruit substrate for ubiquitination and degradation. This protein may have a role in regulating the cell cycle as well as dendrite growth and neuronal migration. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 79791 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |