The FBXO25 Polyclonal Antibody (CAB15150) is a valuable tool for researchers studying FBXO25, a protein associated with cell cycle regulation and ubiquitination processes. This antibody, produced in rabbit hosts, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the FBXO25 protein, this antibody enables precise detection and analysis in various cell types, making it an excellent choice for studies in cell biology and cancer research.FBXO25 is a member of the F-box protein family, known for its role in targeting proteins for degradation through the ubiquitin-proteasome system.
The function of FBXO25 in cell cycle progression and protein turnover highlights its importance in maintaining cellular homeostasis. Research on FBXO25 offers insights into mechanisms underlying cell division, growth regulation, and protein quality control, with implications for understanding diseases such as cancer and neurodegenerative disorders.Overall, the FBXO25 Polyclonal Antibody (CAB15150) provides researchers with a reliable tool for investigating the functions and regulatory pathways involving FBXO25, paving the way for advancements in molecular biology and therapeutic development.
Product Name:
FBXO25 Rabbit Polyclonal Antibody
SKU:
CAB15150
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 142-291 of human FBXO25 (NP_036305.2).
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
26260
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using FBXO25 Rabbit pAb (CAB15150) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
