The FBXL4 Polyclonal Antibody (PACO22856) is a valuable tool for researchers studying the FBXL4 protein, a key player in mitochondrial function and regulation. This antibody, produced in rabbits, is specifically designed for use in Western blot applications and is highly reactive with human samples. By targeting the FBXL4 protein, this antibody allows for the detection and analysis of FBXL4 expression in a variety of cell types, making it essential for studies in mitochondrial biology and related fields.FBXL4 is an important component of the ubiquitin-proteasome system, playing a crucial role in the degradation of proteins involved in mitochondrial homeostasis. Dysregulation of FBXL4 has been associated with mitochondrial diseases and other disorders affecting cellular metabolism.
Thus, understanding the function and regulation of FBXL4 is critical for unraveling the mechanisms underlying these conditions and developing potential therapeutic interventions.By utilizing the FBXL4 Polyclonal Antibody (PACO22856), researchers can gain valuable insights into the role of FBXL4 in mitochondrial biology and its impact on human health. This antibody is a reliable tool for investigating the function of FBXL4 in various cellular processes, providing valuable data that can contribute to advancements in mitochondrial research and the development of targeted therapies for related diseases.
Antibody Name:
Fbxl4 Antibody (PACO22856)
Antibody SKU:
PACO22856
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Drosophila melanogaster
Immunogen:
Peptide sequence around aa.1~5 (M-S-L-L-A) derived from Fruit fly F box and leucine-rich-repeat gene 4.
Form:
Liquid
Storage Buffer:
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Background:
A member of the family of mammalian F-box proteins. F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 aminoacid motif, the F box (so named because cyclin F was one of the first proteins in which this motif was identified) . Some F-box proteins have been shown to be critical for the controlled degradation of cellular regulatory proteins.
