UniProt Protein Function: | FBXL19: Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 16p11.2Cellular Component: SCF ubiquitin ligase complexMolecular Function: protein bindingBiological Process: proteasomal ubiquitin-dependent protein catabolic process |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a member of the Skp1-Cullin-F-box family of E3 ubiquitin ligases. The encoded protein is reported to bind to the transmembrane receptor interleukin 1 receptor-like 1 and regulate its ubiquitination and degradation. This protein has been linked to the regulation of pulmonary inflammation and psoriasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] |
UniProt Code: | Q6PCT2 |
NCBI GenInfo Identifier: | 322510127 |
NCBI Gene ID: | 54620 |
NCBI Accession: | Q6PCT2.3 |
UniProt Secondary Accession: | Q6PCT2,Q8N789, Q9NT14, A8MT10 |
UniProt Related Accession: | Q6PCT2 |
Molecular Weight: | 72,253 Da |
NCBI Full Name: | F-box/LRR-repeat protein 19 |
NCBI Synonym Full Names: | F-box and leucine rich repeat protein 19 |
NCBI Official Symbol: | FBXL19Â Â |
NCBI Official Synonym Symbols: | Fbl19; CXXC11; JHDM1CÂ Â |
NCBI Protein Information: | F-box/LRR-repeat protein 19 |
UniProt Protein Name: | F-box/LRR-repeat protein 19 |
UniProt Synonym Protein Names: | F-box and leucine-rich repeat protein 19 |
Protein Family: | F-box/LRR-repeat protein |
UniProt Gene Name: | FBXL19Â Â |
UniProt Entry Name: | FXL19_HUMAN |