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FBXL14 Rabbit Polyclonal Antibody (CAB17832)

SKU:
CAB17832
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
$167 - $503
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:FBXL14 Rabbit Polyclonal Antibody
SKU:CAB17832
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-418 of human FBXL14 (NP_689654.1).
Sequence:METH ISCL FPEL LAMI FGYL DVRD KGRA AQVC TAWR DAAY HKSV WRGV EAKL HLRR ANPS LFPS LQAR GIRR VQIL SLRR SLSY VIQG MANI ESLN LSGC YNLT DNGL GHAF VQEI GSLR ALNL SLCK QITD SSLG RIAQ YLKG LEVL ELGG CSNI TNTG LLLI AWGL QRLK SLNL RSCR HLSD VGIG HLAG MTRS AAEG CLGL EQLT LQDC QKLT DLSL KHIS RGLT GLRL LNLS FCGG ISDA GLLH LSHM GSLR SLNL RSCD NISD TGIM HLAM GSLR LSGL DVSF CDKV GDQS LAYI AQGL DGLK SLSL CSCH ISDD GINR MVRQ MHGL RTLN IGQC VRIT DKGL ELIA EHLS QLTG IDLY GCTR ITKR GLER ITQL PCLK VLNL GLWQ MTDS EKEA RGDF SPLF TVRT RGSS RR
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:Fbl14; FBXL14
Positive Sample:A-431,HepG2,Mouse thymus,Mouse spleen,Mouse brain,Rat thymus
Conjugate:Unconjugated
Cellular Localization:cytoplasm, cytosol
Calculated MW:46kDa
Observed MW:46kDa

Members of the F-box protein family, such as FBXL14, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).

Purification Method:Affinity purification
Gene ID:144699
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using FBXL14 Rabbit pAb (CAB17832) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.

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