The FBXL14 Polyclonal Antibody (CAB17832) is a valuable tool for research involving FBXL14, a protein that plays a key role in regulating cellular processes such as protein degradation and cell cycle progression. This rabbit-derived antibody is highly specific and reactive with human samples, making it ideal for use in Western blot applications to study the expression and function of FBXL14.FBXL14 is a member of the F-box protein family and is involved in targeting specific proteins for degradation by the proteasome. It has been implicated in various biological processes, including cell growth, differentiation, and apoptosis, making it a promising target for research in areas such as cancer biology and cell signaling pathways.
By using the FBXL14 Polyclonal Antibody, researchers can better understand the role of FBXL14 in cellular processes and disease progression, ultimately leading to potential therapeutic interventions and treatments. Its high specificity and reactivity make it a valuable tool for studies in molecular biology, cancer research, and drug development.
Product Name:
FBXL14 Rabbit Polyclonal Antibody
SKU:
CAB17832
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-418 of human FBXL14 (NP_689654.1).
Members of the F-box protein family, such as FBXL14, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).
Purification Method:
Affinity purification
Gene ID:
144699
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using FBXL14 Rabbit pAb (CAB17832) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
