FBXL12 Rabbit Polyclonal Antibody (CAB14589)
- SKU:
- CAB14589
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | FBXL12 Rabbit Polyclonal Antibody |
SKU: | CAB14589 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-326 of human FBXL12 (NP_060173.1). |
Sequence: | MATL VELP DSVL LEIF SYLP VRDR IRIS RVCH RWKR LVDD RWLW RHVD LTLY TMRP KVMW HLLR RYMA SRLH SLRM GGYL FSGS QAPQ LSPA LLRA LGQK CPNL KRLC LHVA DLSM VPIT SLPS TLRT LELH SCEI SMAW LHKQ QDPT VLPL LECI VLDR VPAF RDEH LQGL TRFR ALRS LVLG GTYR VTET GLDA GLQE LSYL QRLE VLGC TLSA DSTL LAIS RHLR DVRK IRLT VRGL SAPG LAVL EGMP ALES LCLQ GPLV TPEM PSPT EILS SCLT MPKL RVLE LQGL GWEG QEAE KILC KGLP HCMV IVRA CPKE SMDW WM |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | Fbl12; FBXL12 |
Positive Sample: | NIH/3T3,SW480,293T,A-431,HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol, nucleus |
Calculated MW: | 37kDa |
Observed MW: | 37kDa |
Members of the F-box protein family, such as FBXL12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).
Purification Method: | Affinity purification |
Gene ID: | 54850 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |