The FBPC Polyclonal Antibody (PACO53434) is a valuable tool for researchers studying FBPC, a novel protein involved in cell signaling pathways and immune responses. Raised in rabbits, this antibody is highly specific and reactive with human samples, making it ideal for use in various research applications such as Western blotting. The FBPC antibody binds to the protein, allowing for detection and analysis in different cell types, making it a versatile tool for studies in immunology and cancer research.FBPC has been found to play a crucial role in modulating immune responses and regulating cell growth and survival.
Its involvement in these processes makes it a promising target for research into diseases such as cancer, autoimmune disorders, and inflammatory conditions. By understanding the functions of FBPC, researchers can gain insights into potential therapeutic strategies for manipulating immune responses in these disease contexts.Overall, the FBPC Polyclonal Antibody (PACO53434) is an essential tool for researchers investigating the role of FBPC in immune regulation and disease pathology. Its high specificity and reactivity make it a reliable reagent for studying FBPC in various experimental settings.
Antibody Name:
fbpC Antibody (PACO53434)
Antibody SKU:
PACO53434
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:5000
Species Reactivity:
Mycobacterium tuberculosis
Immunogen:
Recombinant Mycobacterium tuberculosis Diacylglycerol acyltransferase/mycolyltransferase Ag85C protein (46-340AA)
Western Blot. Positive WB detected in Recombinant protein. All lanes: fbpC antibody at 2.8µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 37 kDa. Observed band size: 37 kDa.
Background:
The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria to fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine alveolar macrophages (AMs). They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acid, to cell wall arabinogalactan and through the synthesis of alpha,alpha-trehalose dimycolate (TDM, cord factor). They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-trehalose monomycolate (TMM) to another TMM, leading to the formation of TDM (By similarity).
Synonyms:
Diacylglycerol acyltransferase/mycolyltransferase Ag85C (DGAT) (EC 2.3.1.122) (EC 2.3.1.20) (Acyl-CoA:diacylglycerol acyltransferase) (Antigen 85 complex C) (85C) (Ag85C) (Fibronectin-binding protein C) (Fbps C), fbpC, mpt45
UniProt Protein Function:
The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria to fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine alveolar macrophages (AMs). They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan and through the synthesis of alpha,alpha-trehalose dimycolate (TDM, cord factor). They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-trehalose monomycolate (TMM) to another TMM, leading to the formation of TDM ().
