fbpB Antibody (PACO61814)
- SKU:
- PACO61814
- Product Type:
- Antibody
- Reactivity:
- Bacteria
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
fbpB Antibody (PACO61814)
The FBPB Polyclonal Antibody (PAC061814) is a valuable tool for researchers studying FBPB, a protein associated with various cellular processes, including cell growth and metabolism. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the FBPB protein, researchers can detect and analyze its expression in different cell types, making it suitable for investigations in molecular biology and cancer research.FBPB, also known as fructose-1,6-bisphosphatase, plays a crucial role in glucose metabolism and gluconeogenesis.
Its involvement in these metabolic pathways implicates it in various diseases, such as diabetes and metabolic disorders. Understanding the function of FBPB can provide insights into disease mechanisms and potential therapeutic approaches aimed at targeting this protein. Utilizing the FBPB Polyclonal Antibody can enhance research efforts to unravel the complexities of FBPB biology and its implications in health and disease.
| Antibody Name: | fbpB Antibody (PACO61814) |
| Antibody SKU: | PACO61814 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000 |
| Species Reactivity: | Mycobacterium kansasii |
| Immunogen: | Recombinant Mycobacterium kansasii Diacylglycerol acyltransferase/mycolyltransferase Ag85B protein (41-325AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in Recombinant protein. All lanes: fbpB antibody at 3.2µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 50 kDa. Observed band size: 50 kDa. |
| Background: | The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine alveolar macrophages (AMs). They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acid, to cell wall arabinogalactan and through the synthesis of alpha,alpha-trehalose dimycolate (TDM, cord factor). They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-trehalose monomycolate (TMM) to another TMM, leading to the formation of TDM (By similarity). |
| Synonyms: | Diacylglycerol acyltransferase/mycolyltransferase Ag85B (DGAT) (EC 2.3.1.122) (EC 2.3.1.20) (30 kDa extracellular protein) (Acyl-CoA: diacylglycerol acyltransferase) (Antigen 85 complex B) (85B) (Ag85B) (Extracellular alpha-antigen) (Fibronectin-binding protein B) (Fbps B), fbpB |
| UniProt Protein Function: | The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine alveolar macrophages (AMs). They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan and through the synthesis of alpha,alpha-trehalose dimycolate (TDM, cord factor). They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-trehalose monomycolate (TMM) to another TMM, leading to the formation of TDM (). |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P21160 |
| NCBI GenInfo Identifier: | 113655 |
| NCBI Gene ID: | |
| NCBI Accession: | P21160.1 |
| UniProt Secondary Accession: | P21160 |
| UniProt Related Accession: | P21160 |
| Molecular Weight: | 50.6 kDa |
| NCBI Full Name: | Diacylglycerol acyltransferase/mycolyltransferase Ag85B |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | |
| UniProt Protein Name: | Diacylglycerol acyltransferase/mycolyltransferase Ag85B |
| UniProt Synonym Protein Names: | 30 kDa extracellular protein; Acyl-CoA:diacylglycerol acyltransferase; Antigen 85 complex B; 85B; Ag85B; Extracellular alpha-antigen; Fibronectin-binding protein B; Fbps B |
| Protein Family: | Fe(3+)-transport system permease protein |
| UniProt Gene Name: | fbpBÂ Â |
| UniProt Entry Name: | A85B_MYCKA |
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