The FBP1 Polyclonal Antibody (CAB5406) is a valuable tool for researchers studying FBP1, a key enzyme involved in gluconeogenesis and tumor suppression. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the FBP1 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it perfect for investigations in metabolic disorders and cancer research.
FBP1, also known as fructose-1,6-bisphosphatase 1, plays a crucial role in regulating glucose metabolism and suppressing tumor growth. Its function in gluconeogenesis makes it a promising target for understanding metabolic disorders like diabetes, as well as exploring therapeutic approaches for cancer treatment. Unraveling the mechanisms behind FBP1 activity is essential for developing strategies that target glucose metabolism in disease settings.
Product Name:
FBP1 Rabbit Polyclonal Antibody
SKU:
CAB5406
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human FBP1 (NP_000498.2).
Fructose-1,6-bisphosphatase 1, a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis.
Purification Method:
Affinity purification
Gene ID:
2203
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using FBP1 antibody (CAB5406) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
