The FBN2 Polyclonal Antibody (CAB9414) is a valuable tool for researchers studying the Fibrillin-2 protein, which plays a crucial role in the extracellular matrix and elastic fiber formation. This antibody, produced in rabbits, is highly specific to human samples and has been rigorously validated for use in Western blot applications.Fibrillin-2 is essential for maintaining the structural integrity of tissues and organs, particularly in connective tissues such as skin, blood vessels, and lungs. Dysregulation of FBN2 has been implicated in various genetic disorders, including Marfan syndrome and other connective tissue diseases.
By targeting the FBN2 protein, researchers can gain insights into the molecular mechanisms underlying these disorders, as well as potential therapeutic strategies for treating them. The FBN2 Polyclonal Antibody is a reliable tool for exploring the role of Fibrillin-2 in health and disease, making it an invaluable asset for studies in genetics, developmental biology, and regenerative medicine.
Product Name:
FBN2 Rabbit Polyclonal Antibody
SKU:
CAB9414
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 2733-2912 of human FBN2 (NP_001990.2).
The protein encoded by this gene is a component of connective tissue microfibrils and may be involved in elastic fiber assembly. Mutations in this gene cause congenital contractural arachnodactyly.
Purification Method:
Affinity purification
Gene ID:
2201
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using FBN2 Rabbit pAb (CAB9414) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
