The FBLN7 Polyclonal Antibody (PACO36166) is a valuable tool for researchers studying the FBLN7 protein, an extracellular matrix glycoprotein involved in cell adhesion and tissue development. This antibody, produced in rabbits, has high reactivity with human samples and is validated for use in Western blotting applications. By binding specifically to the FBLN7 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for investigations in cell biology and developmental biology.
FBLN7, also known as fibulin-7, plays a crucial role in maintaining tissue integrity and facilitating cell interactions within the extracellular matrix. Its involvement in cell adhesion and migration processes make it a compelling target for research into tissue development, wound healing, and cancer metastasis. Understanding the function of FBLN7 can provide valuable insights into these biological processes and may lead to the development of novel therapeutic strategies for a range of conditions.
Immunohistochemistry of paraffin-embedded human pancreatic cancer using PACO36166 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human gastric cancer using PACO36166 at dilution of 1:100.
Background:
An adhesion molecule that interacts with extracellular matrix molecules in developing teeth and may play important roles in differentiation and maintenance of odontoblasts as well as in dentin formation.
Synonyms:
Fibulin-7 (FIBL-7), FBLN7, TM14
UniProt Protein Function:
FBLN7: An adhesion molecule that interacts with extracellular matrix molecules in developing teeth and may play important roles in differentiation and maintenance of odontoblasts as well as in dentin formation. Belongs to the fibulin family. 4 isoforms of the human protein are produced by alternative splicing.Protein type: Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 2q13Cellular Component: proteinaceous extracellular matrix; focal adhesionMolecular Function: heparin binding; calcium ion bindingBiological Process: cell adhesion
