Fatty Acid Synthase (FASN) Rabbit Polyclonal Antibody (CAB0461)
- SKU:
- CAB0461
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | Fatty Acid Synthase (FASN) Rabbit Polyclonal Antibody |
SKU: | CAB0461 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 2221-2511 of human Fatty Acid Synthase (FASN) (NP_004095.4). |
Sequence: | SLLV NPEG PTLM RLNS VQSS ERPL FLVH PIEG STTV FHSL ASRL SIPT YGLQ CTRA APLD SIHS LAAY YIDC IRQV QPEG PYRV AGYS YGAC VAFE MCSQ LQAQ QSPA PTHN SLFL FDGS PTYV LAYT QSYR AKLT PGCE AEAE TEAI CFFV QQFT DMEH NRVL EALL PLKG LEER VAAA VDLI IKSH QGLD RQEL SFAA RSFY YKLR AAEQ YTPK AKYH GNVM LLRA KTGG AYGE DLGA DYNL SQVC DGKV SVHV IEGD HRTL LEGS GLES IISI IHSS LAEP RVSV REG |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | FAS; OA-519; SDR27X1; Fatty Acid Synthase (FASN) |
Positive Sample: | MCF7,A-549,HeLa,293T,Mouse liver,Mouse thymus,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Melanosome. |
Calculated MW: | 273kDa |
The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.
Purification Method: | Affinity purification |
Gene ID: | 2194 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |