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Fatty Acid Synthase (FASN) Polyclonal Antibody (CAB21398)

SKU:
CAB21398
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
$167 - $635
Frequently bought together:

Description

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Product Name:Fatty Acid Synthase (FASN) Polyclonal Antibody
SKU:CAB21398
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 2221-2511 of human Fatty Acid Synthase (FASN) (NP_004095.4).
Sequence:SLLV NPEG PTLM RLNS VQSS ERPL FLVH PIEG STTV FHSL ASRL SIPT YGLQ CTRA APLD SIHS LAAY YIDC IRQV QPEG PYRV AGYS YGAC VAFE MCSQ LQAQ QSPA PTHN SLFL FDGS PTYV LAYT QSYR AKLT PGCE AEAE TEAI CFFV QQFT DMEH NRVL EALL PLKG LEER VAAA VDLI IKSH QGLD RQEL SFAA RSFY YKLR AAEQ YTPK AKYH GNVM LLRA KTGG AYGE DLGA DYNL SQVC DGKV SVHV IEGD HRTL LEGS GLES IISI IHSS LAEP RVSV REG
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:FAS; OA-519; SDR27X1; N)
Positive Sample:HeLa,MCF7,Mouse liver,Rat liver
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Melanosome.
Calculated MW:273kDa
Observed MW:273kDa

The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.

Purification Method:Affinity purification
Gene ID:2194
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from MCF7, using Fatty Acid Synthase (FASN) Rabbit pAb (CAB21398) at 1:900 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 0.5s.

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