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FATE1 Antibody (PACO38678)

SKU:
PACO38678
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
IHC
IF
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
  • FATE1 Antibody PACO38678
  • FATE1 Antibody PACO38678
  • FATE1 Antibody PACO38678
€359

Description

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FATE1 Antibody (PACO38678)

The FATE1 Monoclonal Antibody (PACO38678) is a powerful tool for researchers studying FATE1, a protein involved in cell fate determination and apoptosis. This antibody, generated using innovative technology, specifically recognizes FATE1 and has been validated for use in a variety of experimental techniques, including immunohistochemistry and flow cytometry.FATE1 is a key player in regulating cell survival and death pathways, making it a promising target for investigating cancer progression and therapy resistance.

By using the FATE1 Antibody, researchers can explore the function and expression levels of FATE1 in different cell types and tissues, providing valuable insights into its role in disease pathogenesis.With its high specificity and sensitivity, the FATE1 Monoclonal Antibody offers researchers a reliable tool for advancing their understanding of FATE1 biology and its implications in cancer research and therapeutics. Order now to enhance your research in cell fate determination and apoptosis pathways.

Antibody Name:FATE1 Antibody (PACO38678)
Antibody SKU:PACO38678
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, IHC, IF
Recommended Dilutions:ELISA:1:2000-1:10000, IHC:1:200-1:500, IF:1:50-1:500
Species Reactivity:Human
Immunogen:Recombinant Human Fetal and adult testis-expressed transcript protein (1-162AA)
Form:Liquid
Storage Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:>95%, Protein G purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Product ImageIHC image of PACO38678 diluted at 1:400 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Product ImageImmunofluorescent analysis of A549 cells using PACO38678 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Product ImageIHC image of PACO38678 diluted at 1:400 and staining in paraffin-embedded human ovarian cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Background:Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER-mitochondria distance and Ca2+ transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis. May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling.
Synonyms:Fetal and adult testis-expressed transcript protein (Cancer/testis antigen 43) (CT43) (Tumor antigen BJ-HCC-2), FATE1, FATE
UniProt Protein Function:FATE1: Protein type: Cancer Testis Antigen (CTA); Membrane protein, integralChromosomal Location of Human Ortholog: Xq28Cellular Component: endoplasmic reticulum; integral to membraneMolecular Function: protein binding
UniProt Protein Details:
NCBI Summary:This gene encodes a cancer-testis antigen that is highly expressed in hepatocellular carcinomas and other tumors and weakly expressed in normal tissues except testis. The protein is strongly expressed in spermatogonia, primary spermatocytes, and Sertoli cells in seminiferous tubules. This protein may have a role in the control of early testicular differentiation and cell proliferation. [provided by RefSeq, Jan 2010]
UniProt Code:Q969F0
NCBI GenInfo Identifier:37078481
NCBI Gene ID:89885
NCBI Accession:Q969F0.1
UniProt Secondary Accession:Q969F0
UniProt Related Accession:Q969F0
Molecular Weight:
NCBI Full Name:Fetal and adult testis-expressed transcript protein
NCBI Synonym Full Names:fetal and adult testis expressed 1
NCBI Official Symbol:FATE1  
NCBI Official Synonym Symbols:CT43; FATE  
NCBI Protein Information:fetal and adult testis-expressed transcript protein; BJ-HCC-2 antigen; cancer/testis antigen 43; fetal and adult testis expressed transcript protein; tumor antigen BJ-HCC-2
UniProt Protein Name:Fetal and adult testis-expressed transcript protein
UniProt Synonym Protein Names:Cancer/testis antigen 43; CT43; Tumor antigen BJ-HCC-2
Protein Family:Fetal and adult testis-expressed transcript protein
UniProt Gene Name:FATE1  
UniProt Entry Name:FATE1_HUMAN
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Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)
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