The FAT3 Polyclonal Antibody (PAC053126) is a valuable tool for researchers studying FAT3, a cell surface protein with essential functions in cell adhesion and signaling. This antibody, generated in rabbits, exhibits high specificity towards human samples and is validated for use in Western blot applications. By specifically binding to FAT3 protein, this antibody enables accurate detection and analysis in various cell types, making it an ideal choice for studies focusing on cell adhesion, migration, and development.
FAT3, also known as a member of the FAT family of cadherins, is a key player in regulating cell-to-cell interactions and tissue organization. Its involvement in essential cellular processes underscores its importance in developmental biology, cancer research, and neurobiology. By targeting FAT3, researchers can gain insights into its role in cell behavior and function, paving the way for potential therapeutic strategies in conditions related to abnormal cell adhesion and migration.
Immunohistochemistry of paraffin-embedded human brain tissue using PACO53126 at dilution of 1:100.
Immunofluorescent analysis of HepG2 cells using PACO53126 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
May play a role in the interactions between neurites derived from specific subsets of neurons during development.
Synonyms:
Protocadherin Fat 3 (hFat3) (Cadherin family member 15) (FAT tumor suppressor homolog 3), FAT3, CDHF15 KIAA1989
UniProt Protein Function:
FAT3: May play a role in the interactions between neurites derived from specific subsets of neurons during development. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 11q14.3Cellular Component: integral to membrane; plasma membraneMolecular Function: calcium ion bindingBiological Process: multicellular organismal development; homophilic cell adhesion
