Fascin/FSCN1 Rabbit Monoclonal Antibody (CAB9566)
- SKU:
- CAB9566
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Fascin/FSCN1 Rabbit Monoclonal Antibody |
SKU: | CAB9566 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 249-362 of human Fascin/FSCN1 (Q16658). |
Sequence: | GKDE LFAL EQSC AQVV LQAA NERN VSTR QGMD LSAN QDEE TDQE TFQL EIDR DTKK CAFR THTG KYWT LTAT GGVQ STAS SKNA SCYF DIEW RDRR ITLR ASNG KFVT SKKN GQ |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | HSN; SNL; p55; FAN1; Fascin/FSCN1 |
Positive Sample: | HeLa,HepG2,Mouse brain,Mouse kidney,Mouse heart,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell projection, Cytoplasm, cytoskeleton, cytosol, filopodium, invadopodium, microvillus. |
Calculated MW: | 55kDa |
Observed MW: | 54kDa |
This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15.
Purification Method: | Affinity purification |
Gene ID: | 6624 |
Clone Number: | ARC1638 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |