The FARS2 Polyclonal Antibody (CAB15246) is a valuable tool for research involving the FARS2 protein, which is a key enzyme involved in mitochondrial protein translation. This antibody is raised in rabbits and is highly reactive with human samples, making it ideal for use in a variety of experimental applications.The FARS2 protein is essential for maintaining mitochondrial function and has been implicated in various diseases, including neuromuscular disorders and mitochondrial respiratory chain deficiencies. By targeting the FARS2 protein, researchers can better understand its role in cellular health and disease progression.
This antibody is validated for use in Western blot applications, allowing for the detection and analysis of the FARS2 protein in different cell types. Its high specificity and sensitivity make it a reliable tool for studies in mitochondrial biology, neurodegenerative diseases, and metabolism research.Overall, the FARS2 Polyclonal Antibody is a valuable resource for scientists looking to investigate the function and regulation of the FARS2 protein, with potential implications for understanding and treating a range of mitochondrial-related disorders.
Product Name:
FARS2 Rabbit Polyclonal Antibody
SKU:
CAB15246
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human FARS2 (NP_006558.1).
This gene encodes a protein that transfers phenylalanine to its cognate tRNA. This protein localizes to the mitochondrion and plays a role in mitochondrial protein translation. Mutations in this gene can cause combined oxidative phosphorylation deficiency 14 (Alpers encephalopathy). Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
10667
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using FARS2 Rabbit pAb (CAB15246) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.