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FARP2 Antibody (PACO09233)

SKU:
PACO09233
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€459
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Description

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FARP2 Antibody (PACO09233)

The FARP2 Monoclonal Antibody (PACO09233) is a powerful tool for researchers studying FARP2, a protein involved in synaptic function and neuronal development. This antibody, produced in mice, demonstrates high specificity for FARP2 in human samples and has been validated for use in various applications, including Western blot and immunofluorescence.FARP2, also known as a guanine nucleotide exchange factor, plays a crucial role in the regulation of neuronal signaling pathways and synaptic plasticity.

By targeting FARP2, researchers can gain valuable insights into the mechanisms underlying neurological disorders such as Alzheimer's disease, schizophrenia, and autism spectrum disorders. The ability to study FARP2 expression and localization in different cell types makes this antibody an essential tool for neuroscience research.

Antibody Name:FARP2 Antibody (PACO09233)
Antibody SKU:PACO09233
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, IHC
Recommended Dilutions:
Species Reactivity:Human, Mouse, Rat
Immunogen:Human FARP2
Form:Liquid
Storage Buffer:PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method:Antigen Affinity Purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:FERM, RhoGEF and pleckstrin domain protein 2;FARP2;FIR;FRG;KIAA0793;PLEKHC3 ;
UniProt Protein Function:FARP2: Rho-guanine nucleotide exchange factor that activates RAC1. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Cell development/differentiation; GEF; GEF, Rac/Rho; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2q37.3

Cellular Component: cytoplasm; cytoskeleton; cytosol

Molecular Function:cytoskeletal protein binding; Rac guanyl-nucleotide exchange factor activity; Rho guanyl-nucleotide exchange factor activity

Biological Process: actin cytoskeleton reorganization; cell adhesion; hair cycle process; neuron remodeling; osteoclast differentiation; positive regulation of GTPase activity; Rac protein signal transduction; regulation of integrin activation; regulation of Rho protein signal transduction

UniProt Code:O94887
NCBI GenInfo Identifier:545478372
NCBI Gene ID:9855
NCBI Accession:NP_001269912.1
UniProt Secondary Accession:O94887,Q53QM5, Q8WU27, Q9UFE7, B7Z6J8, F5GZ84,
UniProt Related Accession:O94887
Molecular Weight:119 kDa
NCBI Full Name:FERM, ARHGEF and pleckstrin domain-containing protein 2 isoform b
NCBI Synonym Full Names:FERM, ARH/RhoGEF and pleckstrin domain protein 2
NCBI Official Symbol:FARP2  
NCBI Official Synonym Symbols:FIR; FRG; PLEKHC3  
NCBI Protein Information:FERM, ARHGEF and pleckstrin domain-containing protein 2; FERM, RhoGEF and pleckstrin domain-containing protein 2
UniProt Protein Name:FERM, ARHGEF and pleckstrin domain-containing protein 2
UniProt Synonym Protein Names:FERM domain-including RhoGEF; FIR; FERM, RhoGEF and pleckstrin domain-containing protein 2; Pleckstrin homology domain-containing family C member 3; PH domain-containing family C member 3
UniProt Gene Name:FARP2  

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