FARP2 Antibody (PACO00805)
- SKU:
- PACO00805
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
FARP2 Antibody (PACO00805)
The FARP2 Polyclonal Antibody (PACO00805) is a vital tool for researchers interested in studying FARP2, a protein involved in neuronal development and synaptic signaling. This antibody, produced in rabbits, has high specificity for human samples and has been rigorously validated for Western blot applications. By binding to FARP2, the antibody allows for precise detection and analysis of this crucial protein in various cell types, making it an essential asset for studies in neuroscience and neurobiology.FARP2, also known as Fer-activated protein kinase 2, plays a key role in regulating dendritic spine formation and neuronal connectivity, making it a target of interest in research on neurological disorders and cognitive function.
Understanding the function and regulation of FARP2 is essential for unraveling the mechanisms underlying brain development and synaptic plasticity, with potential implications for the treatment of neurological conditions such as autism and schizophrenia.Overall, the FARP2 Polyclonal Antibody offers a reliable and effective tool for researchers seeking to explore the role of FARP2 in the brain, providing valuable insights into the complex processes that govern neuronal signaling and connectivity.
| Antibody Name: | FARP2 Antibody |
| Antibody SKU: | PACO00805 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IF |
| Recommended Dilutions: | WB:1:500-1:2000, IF:1:200-1:1000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | synthesized peptide derived from the Internal region of human FIR. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | FARP2; KIAA0793; PLEKHC3; FERM; RhoGEF and pleckstrin domain-containing protein 2; FERM domain including RhoGEF; FIR; Pleckstrin homology domain-containing family C member 3; PH domain-containing family C member 3 |
| UniProt Protein Function: | FARP2: Rho-guanine nucleotide exchange factor that activates RAC1. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cell development/differentiation; GEF; GEF, Rac/Rho; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 2q37.3 Cellular Component: cytoplasm; cytoskeleton; cytosol Molecular Function:cytoskeletal protein binding; Rac guanyl-nucleotide exchange factor activity; Rho guanyl-nucleotide exchange factor activity Biological Process: actin cytoskeleton reorganization; cell adhesion; hair cycle process; neuron remodeling; osteoclast differentiation; positive regulation of GTPase activity; Rac protein signal transduction; regulation of integrin activation; regulation of Rho protein signal transduction |
| UniProt Code: | O94887 |
| NCBI GenInfo Identifier: | 545478372 |
| NCBI Gene ID: | 9855 |
| NCBI Accession: | NP_001269912.1 |
| UniProt Secondary Accession: | O94887,Q53QM5, Q8WU27, Q9UFE7, B7Z6J8, F5GZ84, |
| UniProt Related Accession: | O94887 |
| Molecular Weight: | 119 kDa |
| NCBI Full Name: | FERM, ARHGEF and pleckstrin domain-containing protein 2 isoform b |
| NCBI Synonym Full Names: | FERM, ARH/RhoGEF and pleckstrin domain protein 2 |
| NCBI Official Symbol: | FARP2Â Â |
| NCBI Official Synonym Symbols: | FIR; FRG; PLEKHC3Â Â |
| NCBI Protein Information: | FERM, ARHGEF and pleckstrin domain-containing protein 2; FERM, RhoGEF and pleckstrin domain-containing protein 2 |
| UniProt Protein Name: | FERM, ARHGEF and pleckstrin domain-containing protein 2 |
| UniProt Synonym Protein Names: | FERM domain-including RhoGEF; FIR; FERM, RhoGEF and pleckstrin domain-containing protein 2; Pleckstrin homology domain-containing family C member 3; PH domain-containing family C member 3 |
| UniProt Gene Name: | FARP2Â Â |
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