The FAR2 Antibody (PACO16314) is a highly specific and sensitive tool for researchers studying the FAR2 protein, an enzyme involved in fatty acid metabolism. This polyclonal antibody, generated in rabbits, shows strong reactivity with human samples and is suitable for use in Western blot applications. By targeting the FAR2 protein, this antibody allows for the detection and analysis of FAR2 expression in various cell types, making it ideal for investigations in lipid metabolism, obesity, and related metabolic disorders.The FAR2 enzyme plays a critical role in regulating fatty acid metabolism and energy balance, making it a promising target for research into metabolic diseases such as obesity, diabetes, and cardiovascular disorders.
Understanding the function and regulation of FAR2 is essential for developing therapeutic interventions aimed at modulating lipid metabolism and improving metabolic health.Overall, the FAR2 Antibody (PACO16314) offers researchers a valuable tool for investigating the role of the FAR2 enzyme in metabolic processes and associated diseases, paving the way for potential advancements in the treatment and management of metabolic disorders.
Antibody Name:
FAR2 Antibody (PACO16314)
Antibody SKU:
PACO16314
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:50-1:200
Species Reactivity:
Human, Mouse
Immunogen:
Fusion protein of human FAR2
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using PACO16314(FAR2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO16314(FAR2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200).
Background:
This gene belongs to the short chain dehydrogenase/reductase superfamily. It encodes a reductase enzyme involved in the first step of wax biosynthesis wherein fatty acid, are converted to fatty alcohols. The encoded peroxisomal protein utilizes saturated fatty acid, of 16 or 18 carbons as preferred substrates. Alternatively spliced transcript variants have been observed for this gene. Related pseudogenes have been identified on chromosomes 2, 14 and 22.
Synonyms:
fatty acyl CoA reductase 2
UniProt Protein Function:
MLSTD1: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. The preferred substrates are C16, C18, C18:1 and C18:2 but low activity can be observed with C10-C14 substrates. Belongs to the fatty acyl-CoA reductase family.Protein type: Oxidoreductase; Membrane protein, integral; EC 1.2.1.n2; Membrane protein, multi-passChromosomal Location of Human Ortholog: 12p11.22Cellular Component: peroxisomal membrane; peroxisomal matrix; endoplasmic reticulum membrane; integral to membrane; peroxisomeMolecular Function: long-chain-fatty-acyl-CoA reductase activityBiological Process: cellular lipid metabolic process; ether lipid biosynthetic process
UniProt Protein Details:
NCBI Summary:
This gene belongs to the short chain dehydrogenase/reductase superfamily. It encodes a reductase enzyme involved in the first step of wax biosynthesis wherein fatty acids are converted to fatty alcohols. The encoded peroxisomal protein utilizes saturated fatty acids of 16 or 18 carbons as preferred substrates. Alternatively spliced transcript variants have been observed for this gene. Related pseudogenes have been identified on chromosomes 2, 14 and 22. [provided by RefSeq, Nov 2012]
