The FAP1 Rabbit Monoclonal Antibody is a valuable tool for researchers studying FAP1, a protein involved in various cellular processes such as cell migration, invasion, and inflammation. This antibody, developed using rabbit monoclonal technology, is highly specific and sensitive for detecting FAP1 in human samples.With its high reactivity and specificity, this antibody is ideal for use in Western blotting, immunofluorescence, and immunohistochemistry applications. By binding to FAP1, researchers can accurately detect and quantify the protein in different cell types and tissues, making it an essential tool for studies in cancer research and immunology.
FAP1, also known as fibroblast activation protein alpha, is a promising target for therapeutic interventions in cancer due to its involvement in tumor progression and metastasis. By understanding the role of FAP1 in these processes, researchers can develop novel treatment strategies and improve patient outcomes in various cancer types.Overall, the FAP1 Rabbit Monoclonal Antibody offers researchers a reliable and effective tool for studying FAP1 and its implications in cancer biology, making it a valuable asset in the field of cancer research.
Cell membrane, Cell projection, Cell surface, Cytoplasm, Membrane, Secreted, Single-pass type II membrane protein, Single-pass type II membrane protein, invadopodium membrane, lamellipodium membrane, ruffle membrane.
Calculated MW:
88kDa
Observed MW:
88kDa
The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
2191
Clone Number:
ARC0634
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from U-87MG cells, using Fibroblast activation protein-α (FAP) Rabbit mAb (CAB11572) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
