FANCL Rabbit Polyclonal Antibody (CAB6812)
- SKU:
- CAB6812
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | FANCL Rabbit Polyclonal Antibody |
SKU: | CAB6812 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-255 of human FANCL (NP_060532.2). |
Sequence: | MAVT EASL LRQC PLLL PQNR SKTV YEGF ISAQ GRDF HLRI VLPE DLQL KNAR LLCS WQLR TILS GYHR IVQQ RMQH SPDL MSFM MELK MLLE VALK NRQE LYAL PPPP QFYS SLIE EIGT LGWD KLVY ADTC FSTI KLKA EDAS GREH LITL KLKA KYPA ESPD YFVD FPVP FCAS WTPQ SSLI SIYS QFLA AIES LKAF WDVM DEID EKTW VLEP EKPP RSAT ARRI ALGN NVSI NIEV DPRH PTML PECF FLG |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 |
Synonyms: | POG; PHF9; FAAP43; FANCL |
Positive Sample: | Mouse thymus |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 43kDa |
Observed MW: | 38kDa |
This gene encodes a ubiquitin ligase that is a member of the Fanconi anemia complementation group (FANC). Members of this group are related by their assembly into a common nuclear protein complex rather than by sequence similarity. This gene encodes the protein for complementation group L that mediates monoubiquitination of FANCD2 as well as FANCI. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 55120 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |