FANCI Rabbit Polyclonal Antibody (CAB3447)
- SKU:
- CAB3447
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Cycle
Description
Product Name: | FANCI Rabbit Polyclonal Antibody |
SKU: | CAB3447 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1061-1328 of human FANCI (NP_001106849.1). |
Sequence: | DQDV EVEK TNHF AIVN LRTA APTV CLLV LSQA EKVL EEVD WLIT KLKG QVSQ ETLS EEAS SQAT LPNQ PVEK AIIM QLGT LLTF FHEL VQTA LPSG SCVD TLLK DLCK MYTT LTAL VRYY LQVC QSSG GIPK NMEK LVKL SGSH LTPL CYSF ISYV QNKS KSLN YTGE KKEK PAAV ATAM ARVL RETK PIPN LIFA IEQY EKFL IHLS KKSK VNLM QHMK LSTS RDFK IKGN ILDM VLRE DGED ENEE GTAS EHGG QNKE PAKK KRKK |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | KIAA1794; FANCI |
Positive Sample: | HeLa,293T,MCF7 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 149kDa |
Observed MW: | 149kDa |
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group I. Alternative splicing results in two transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 55215 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |