FANCA Rabbit Monoclonal Antibody (CAB9529)
- SKU:
- CAB9529
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
Product Name: | FANCA Rabbit Monoclonal Antibody |
SKU: | CAB9529 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 2-104 of human FANCA (O15360). |
Sequence: | SDSW VPNS ASGQ DPGG RRRA WAEL LAGR VKRE KYNP ERAQ KLKE SAVR LLRS HQDL NALL LEVE GPLC KKLS LSKV IDCD SSEA YANH SSSF IGSA LQDQ ASR |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | FA; FA1; FAA; FAH; FA-H; FACA; FANCH; FANCA |
Positive Sample: | HeLa,HT-29,293T |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus |
Calculated MW: | 163kDa |
Observed MW: | 163kDa |
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are the most common cause of Fanconi anemia.
Purification Method: | Affinity purification |
Gene ID: | 2175 |
Clone Number: | ARC1620 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |