The FAM53B Polyclonal Antibody (PACO35446) is a valuable tool for researchers studying FAM53B, a protein involved in cell growth and differentiation. This antibody is produced in rabbits and has high reactivity with human samples, making it suitable for a variety of research applications.FAM53B is known for its role in cell signaling pathways that regulate proliferation and differentiation. Its overexpression has been linked to cancer progression and poor prognosis in certain types of tumors. By targeting this protein with the FAM53B Polyclonal Antibody, researchers can gain insights into the molecular mechanisms underlying these processes.
Validated for use in Western blotting, the FAM53B Polyclonal Antibody allows for the detection and analysis of FAM53B protein levels in different cell types. This makes it an essential tool for studies in cancer biology, developmental biology, and other fields where FAM53B function is of interest. By understanding the role of FAM53B in cellular processes, researchers can potentially identify new therapeutic targets for treating diseases such as cancer.
Western blot. All lanes: FAM53B antibody at 2µg/ml. Lane 1: MCF-7 whole cell lysate. Lane 2: A549 whole cell lysate. Lane 3: HCT116 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 46, 34 kDa. Observed band size: 46 kDa.
Immunohistochemistry of paraffin-embedded human breast cancer using PACO35446 at dilution of 1:100.
Background:
Acts as a regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) nuclear localization.
Synonyms:
Protein FAM53B (Protein simplet), FAM53B, KIAA0140 SMP
UniProt Protein Function:
FAM53B: Belongs to the FAM53 family. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 10q26.13
