The FAM111B Polyclonal Antibody (PACO05958) is a valuable tool for researchers studying FAM111B, a protein involved in DNA replication and cell cycle regulation. This antibody, generated in rabbits, has high specificity for human samples and is validated for use in Western blot applications. By targeting the FAM111B protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an essential component for studies in genetics and cancer research.FAM111B is a crucial player in maintaining genomic stability and ensuring proper cell division, making it a noteworthy candidate for investigation in diseases such as cancer and genetic disorders.
Understanding the functions and interactions of FAM111B can provide insights into the mechanisms underlying oncogenesis and genomic instability, paving the way for the development of targeted therapies and diagnostic tools.Overall, the FAM111B Polyclonal Antibody (PACO05958) serves as a reliable tool for researchers seeking to unravel the complexities of genomic maintenance and cell cycle regulation, offering valuable insights into the role of FAM111B in health and disease.
Antibody Name:
FAM111B Antibody (PACO05958)
Antibody SKU:
PACO05958
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:5000, IHC:1:100-1:300
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from the Internal region of human FAM111B.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
FAM111B; CANP; Protein FAM111B; Cancer-associated nucleoprotein
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein with a trypsin-like cysteine/serine peptidase domain in the C-terminus. Mutations in this gene are associated with an autosomal dominant form of hereditary fibrosing poikiloderma (HFP). Affected individuals display mottled pigmentation, telangiectasia, epidermal atrophy, tendon contractures, and progressive pulmonary fibrosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A paralog of this gene which also has a trypsin?like peptidase domain, FAM111A, is located only 16 kb from this gene on human chromosome 11q12.1. [provided by RefSeq, Apr 2014]
