The FADS2 Polyclonal Antibody (CAB10270) is a valuable tool for research involving FADS2, an essential enzyme involved in the synthesis of omega-3 and omega-6 unsaturated fatty acids. This antibody, produced in rabbits, is highly specific for detecting FADS2 in human samples and has been validated for use in Western blot applications. By binding to the FADS2 protein, this antibody enables precise detection and analysis in various cell types, making it an ideal choice for studies in lipid metabolism, nutritional research, and lipid-related disorders.FADS2, also known as fatty acid desaturase 2, is a key player in the biosynthesis of polyunsaturated fatty acids, which are crucial for maintaining cell membrane structure and function.
Dysregulation of FADS2 has been linked to various health issues, including cardiovascular diseases, inflammatory conditions, and metabolic disorders. Understanding the role of FADS2 in lipid metabolism is essential for developing targeted therapies and interventions aimed at preventing or treating these health complications.Overall, the FADS2 Polyclonal Antibody (CAB10270) offers researchers a reliable tool for studying the functions and regulatory mechanisms of FADS2 in health and disease. Its high specificity and sensitivity make it a valuable asset for unraveling the complex interplay of fatty acid metabolism in various physiological and pathological conditions.
Product Name:
FADS2 Rabbit Polyclonal Antibody
SKU:
CAB10270
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-131 of human FADS2 (NP_004256.1).
The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
9415
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using FADS2 Rabbit pAb (CAB10270) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
