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FABP4 Monoclonal Antibody [P3F4AT] (CPAB0533)

SKU:
CPAB0533
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG1
Clone:
P3F4AT
Applications:
WB
ELISA
€149
Frequently bought together:

Description

system_update_alt Datasheet

FABP4 Monoclonal Antibody [P3F4AT] (CPAB0533)

The FABP4 Polyclonal Antibody (CPAB0533) is a valuable tool for researchers studying FABP4, a key protein involved in lipid metabolism and inflammation. This antibody, generated in rabbits, shows high specificity and sensitivity for detecting FABP4 in human samples, making it ideal for Western blot applications.FABP4, also known as fatty acid-binding protein 4, plays a crucial role in lipid transport and metabolism in adipocytes and macrophages. It is also associated with the regulation of insulin sensitivity and inflammation, making it a potential target for therapeutic interventions in metabolic disorders and cardiovascular diseases.

By using the FABP4 Polyclonal Antibody, researchers can gain valuable insights into the role of FABP4 in various biological processes and diseases, paving the way for the development of novel treatment strategies and diagnostic tools. Its reliability and performance make it a valuable asset for studies in lipid metabolism, obesity, diabetes, and cardiovascular health.

Product Name:FABP4 Antibody
Product Sku:CPAB0533
Size:5μg
Host Species:Mouse
Immunogen:Anti-human FABP4 mAb is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human FABP4 amino acids 1-132 purified from Ecoli.
Clone:P3F4AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:FABP4 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG1
Background:Adipocyte fatty acid binding protein FABP4 is a 15 kDa member of the intracellular fatty acid binding protein (FABP) family, which is known for the ability to bind fatty acids and related compounds (bile acids or retinoids) in an internal cavity. FABP4 is expressed in a differentiation-dependent fashion in adipocytes and is a critical gene in the regulation of the biological function of these cells. In mice, targeted mutations in FABP4 provide significant protection from hyperinsulinemia and insulin resistance in the context of both dietary and genetic obesity. Adipocytes obtained from FABP4-deficient mice also have reduced efficiency of ipolysis in vitro and in vivo, and these mice exhibited moderately improved systemic dyslipidemia. Recent studies also demonstrated FABP4 expression in macrophages upon differentiation and activation.
Synonyms:Fatty acid-binding protein adipocyte, AFABP, Fatty acid-binding protein 4, Adipocyte lipid-binding protein, ALBP, A-FABP, FABP4.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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