The FA2H Polyclonal Antibody (CAB13874) is a highly specific research tool designed for studies involving the FA2H protein. FA2H is an enzyme involved in the biosynthesis of fatty acids and has been implicated in various cellular processes, including myelin formation in the nervous system. This antibody, produced in rabbits, has been rigorously validated for use in Western blot applications and exhibits high reactivity with human samples. By specifically binding to the FA2H protein, researchers can accurately detect and analyze FA2H expression in different cell types.
This makes the antibody an ideal tool for research in neurology, lipid metabolism, and myelin disorders.The FA2H Polyclonal Antibody is essential for investigating the role of FA2H in lipid synthesis and neurological disorders, providing valuable insights into potential therapeutic targets for conditions such as demyelinating diseases and neurodegenerative disorders. Its high specificity and sensitivity make it a valuable tool for scientists working in the fields of neuroscience, biochemistry, and drug discovery.
Product Name:
FA2H Rabbit Polyclonal Antibody
SKU:
CAB13874
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 95-170 of human FA2H (NP_077282.3).
This gene encodes a protein that catalyzes the synthesis of 2-hydroxysphingolipids, a subset of sphingolipids that contain 2-hydroxy fatty acids. Sphingolipids play roles in many cellular processes and their structural diversity arises from modification of the hydrophobic ceramide moiety, such as by 2-hydroxylation of the N-acyl chain, and the existence of many different head groups. Mutations in this gene have been associated with leukodystrophy dysmyelinating with spastic paraparesis with or without dystonia.
Purification Method:
Affinity purification
Gene ID:
79152
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using FA2H Rabbit pAb (CAB13874) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
