Factor IX/F9 Rabbit Polyclonal Antibody (CAB1578)
- SKU:
- CAB1578
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cardiovascular
Description
Product Name: | Factor IX/F9 Rabbit Polyclonal Antibody |
SKU: | CAB1578 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-192 of human Factor IX / F9 (NP_000124.1). |
Sequence: | TVFL DHEN ANKI LNRP KRYN SGKL EEFV QGNL EREC MEEK CSFE EARE VFEN TERT TEFW KQYV DGDQ CESN PCLN GGSC KDDI NSYE CWCP FGFE GKNC ELDV TCNI KNGR CEQF CKNS ADNK VVCS CTEG YRLA ENQK SCEP AVPF PCGR VSVS QTSK LTRA |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | FIX; P19; PTC; HEMB; THPH8; F9 p22; Factor IX / F9 |
Positive Sample: | Human plasma |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 52kDa |
Observed MW: | 52kDa/66kDa |
This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing.
Purification Method: | Affinity purification |
Gene ID: | 2158 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |