The F12 Antibody (PAC051486) from Assay Genie is a high-quality polyclonal antibody specifically designed for research involving F12, a crucial factor in the coagulation cascade. This antibody, produced in rabbits, has been extensively validated for use in a variety of applications, with a particular focus on Western blotting.F12, also known as coagulation factor XII, plays a crucial role in the intrinsic pathway of blood coagulation. Dysregulation of F12 has been implicated in various coagulation disorders and thrombotic events, making it a key target for research in hemostasis and thrombosis.
This antibody binds specifically to the F12 protein, allowing for accurate detection and analysis in a wide range of sample types. Its high reactivity with human samples makes it an ideal tool for researchers studying coagulation disorders, thrombosis, and other related conditions.By using the F12 Antibody from Assay Genie, researchers can gain valuable insights into the role of F12 in the coagulation cascade, paving the way for the development of novel therapies and diagnostic tools for coagulation-related disorders.
Antibody Name:
F12 Antibody (PACO51486)
Antibody SKU:
PACO51486
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Pig
Immunogen:
Recombinant Pig Coagulation factor XII protein (20-371AA)
Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa (By similarity).
Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa.
