F11R Rabbit Polyclonal Antibody (CAB1241)
- SKU:
- CAB1241
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | F11R Rabbit Polyclonal Antibody |
SKU: | CAB1241 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 28-238 of human JAM-A/CD321/F11R (NP_058642.1). |
Sequence: | SVTV HSSE PEVR IPEN NPVK LSCA YSGF SSPR VEWK FDQG DTTR LVCY NNKI TASY EDRV TFLP TGIT FKSV TRED TGTY TCMV SEEG GNSY GEVK VKLI VLVP PSKP TVNI PSSA TIGN RAVL TCSE QDGS PPSE YTWF KDGI VMPT NPKS TRAF SNSS YVLN PTTG ELVF DPLS ASDT GEYS CEAR NGYG TPMT SNAV RMEA VERN VGV |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | JAM; KAT; JAM1; JAMA; JCAM; CD321; PAM-1; JAM-A/CD321/F11R |
Positive Sample: | HepG2,SKOV3,Mouse lung,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Single-pass type I membrane protein, tight junction. |
Calculated MW: | 33kDa |
Observed MW: | 37kDa |
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.
Purification Method: | Affinity purification |
Gene ID: | 50848 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |