Ezrin Rabbit Monoclonal Antibody (CAB19048)
- SKU:
- CAB19048
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Ezrin Rabbit Monoclonal Antibody |
SKU: | CAB19048 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 300-400 of human Ezrin (P15311). |
Sequence: | IEVQ QMKA QARE EKHQ KQLE RQQL ETEK KRRE TVER EKEQ MMRE KEEL MLRL QDYE EKTK KAER ELSE QIQR ALQL EEER KRAQ EEAE RLEA DRMA ALRA K |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | CVL; CVIL; VIL2; HEL-S-105; Ezrin |
Positive Sample: | HCT116 |
Conjugate: | Unconjugated |
Cellular Localization: | Apical cell membrane, Cell projection, Cytoplasm, Cytoplasmic side, Peripheral membrane protein, cell cortex, cytoskeleton, microvillus membrane, ruffle membrane. |
Calculated MW: | 69kDa |
Observed MW: | 80kDa |
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.
Purification Method: | Affinity purification |
Gene ID: | 7430 |
Clone Number: | ARC0392 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |