The Ezrin Rabbit Monoclonal Antibody (CAB19048) is a cutting-edge tool for researchers studying the protein Ezrin, a key regulator of cell structure and function. This highly specific antibody, produced in rabbits, is optimized for use in a variety of applications, including Western blotting and immunofluorescence.Ezrin is a critical component of the cytoskeleton and plays a crucial role in cell adhesion, migration, and signaling. Dysregulation of Ezrin has been implicated in various diseases, including cancer and metastasis.
By targeting Ezrin with this monoclonal antibody, researchers can better understand its function and potential as a therapeutic target.With its high reactivity and specificity for Ezrin, this antibody is an invaluable tool for studies in cell biology, cancer research, and drug development. By enabling the detection and analysis of Ezrin in different cell types and tissues, this antibody opens up new avenues for research into the mechanisms underlying disease progression and potential therapeutic interventions.
Product Name:
Ezrin Rabbit Monoclonal Antibody
SKU:
CAB19048
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 300-400 of human Ezrin (P15311).
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.
Purification Method:
Affinity purification
Gene ID:
7430
Clone Number:
ARC0392
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from HCT116 cells, using Ezrin Rabbit mAb (CAB19048) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
