The EZH1 Polyclonal Antibody (CAB15272) is a valuable tool for researchers studying EZH1, a histone methyltransferase involved in epigenetic regulation. This antibody, raised in rabbits, is highly specific to human EZH1 samples and is suitable for use in Western blot applications. By binding to the EZH1 protein, this antibody allows for the detection and analysis of EZH1 expression in a variety of cell types.EZH1 plays a crucial role in gene regulation and chromatin remodeling, making it a key player in various cellular processes such as development, differentiation, and disease.
Research on EZH1 is important for understanding its function in cancer, stem cell biology, and other epigenetic pathways. The EZH1 Polyclonal Antibody provides researchers with a reliable tool to further explore the role of EZH1 in these contexts and uncover its potential therapeutic implications.
Product Name:
EZH1 Rabbit Polyclonal Antibody
SKU:
CAB15272
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 160-270 of EZH1 (NP_001982.2).
EZH1 is a component of a noncanonical Polycomb repressive complex-2 (PRC2) that mediates methylation of histone H3 (see MIM 602812) lys27 (H3K27) and functions in the maintenance of embryonic stem cell pluripotency and plasticity (Shen et al., 2008 [PubMed 19026780]).
Purification Method:
Affinity purification
Gene ID:
2145
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from RAW264.7 cells, using EZH1 Rabbit pAb (CAB15272) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
