The EYA2 Polyclonal Antibody (CAB15055) is a valuable tool for researchers studying the EYA2 protein, a transcriptional activator and tyrosine phosphatase involved in various cellular processes, including development, DNA repair, and cell survival. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the EYA2 protein, this antibody allows for the detection and analysis of EYA2 expression in different cell types, making it ideal for studies in developmental biology, cancer research, and DNA damage response mechanisms.
EYA2 is known to interact with a variety of transcription factors, chromatin modifiers, and DNA repair proteins, influencing gene expression and cellular functions. Its role in regulating cell proliferation, differentiation, and apoptosis highlights its importance in normal development and disease progression. Research into the function and regulation of EYA2 is essential for understanding its impact on various biological processes and identifying potential therapeutic targets for conditions such as cancer, developmental disorders, and DNA damage-related diseases.
Product Name:
EYA2 Rabbit Polyclonal Antibody
SKU:
CAB15055
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 300-400 of human EYA2 (NP_005235.3).
This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may be post-translationally modified and may play a role in eye development. A similar protein in mice can act as a transcriptional activator. Alternative splicing results in multiple transcript variants, but the full-length natures of all of these variants have not yet been determined.
Purification Method:
Affinity purification
Gene ID:
2139
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using EYA2 Rabbit pAb (CAB15055) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
