The EYA1 Polyclonal Antibody (CAB9534) is a valuable tool for researchers studying the EYA1 protein, a key regulator of gene expression and development. This antibody, generated in rabbits, has high reactivity towards human samples and is specifically validated for use in Western blot applications. By binding to the EYA1 protein, this antibody allows for detailed detection and analysis in a variety of cell types, making it ideal for investigations in developmental biology, cancer research, and gene regulation studies.EYA1 is known for its role in multiple biological processes, including eye development, organogenesis, and cell proliferation.
Dysregulation of EYA1 has been linked to various human diseases, such as congenital cataracts and cancer. By studying the function and expression of EYA1 using this antibody, researchers can gain insights into the underlying mechanisms of these conditions and potentially identify therapeutic targets for future treatments.Overall, the EYA1 Polyclonal Antibody (CAB9534) offers researchers a reliable tool for investigating the complex functions of EYA1 in various biological contexts, paving the way for advancements in molecular biology and disease research.
Product Name:
EYA1 Rabbit Polyclonal Antibody
SKU:
CAB9534
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human EYA1 (NP_000494.2).
This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may play a role in the developing kidney, branchial arches, eye, and ear. Mutations of this gene have been associated with branchiootorenal dysplasia syndrome, branchiootic syndrome, and sporadic cases of congenital cataracts and ocular anterior segment anomalies. A similar protein in mice can act as a transcriptional activator. Alternatively spliced transcript variants have been identified for this gene.
Purification Method:
Affinity purification
Gene ID:
2138
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using EYA1 Rabbit pAb (CAB9534) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
